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A distinct signaling pathway called TNF-α drives the transformation of epithelial cells into aggressive tumor cells. During cancer progression, cells activate their own TNF-α program and become invasive. This finding could help to improve early detection and treatment of patients with cancers in skin, esophagus, bladder or colon, as UZH researchers state.
The recent publication spearheaded by Peter Renz from the Sendoel group in Nature has also been featured by Tagesanzeiger and the UZH news.
Original Article in Nature
UZH News Article in German and English
Article in Tages-Anzeiger (German only)
