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The projects are focused on the preclinical development and validation of aortic tissue-engineered heart valves suitable for minimally-invasive applications. These prostheses have the unique ability to transform into a fully autologous valve within the body and last for life. In details, the project aims at engineering a novel xenogeneic-free decellularized human matrix and a bioresorbable stent, and finally apply an unconventional bioengineering approach combining in-vitro, in-silico, and in-vivo tissue engineering methods.
This Group is part of the ERC project TAVI4Life of Prof. Maximilian Emmert